Merial Limited

Centragard™ for Cats

Merial Limited
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Centragard™ Topical Solution for Cats
Product Information
Centragard™ Topical Solution is a broad-spectrum once a month topical application that prevents heartworm disease and treats and controls hookworms, roundworms and tapeworms in cats.
Cats (at least 7 weeks of age and weighing at least 1.8 lbs) 
Generic Name
Eprinomectin, Praziquantel
Brand Name
Drug Class
Topical avermectin, anticestodal combination antiparasitic
Boehringer Ingelheim
Product Description
Centragard™ Topical Solution is a yellow (colorless to pale yellow-brown) liquid.
  • Once a month application that works systemically to prevent heartworm disease
  • No pilling required
  • Treats and controls hookworms (A. tubaeforme, A. braziliense), roundworms (T. cati), and tapeworms (D. caninum, E. multiocularis)  when given routinely every 30 days
  • Targets immature stages of roundworms and hookworms
  • Approved for cats 7+ weeks of age, weighing more than 1.8 lbs
Active Ingredients
Eprinomectin, Praziquantel
Centragard™ Topical Solution should be applied as directed by your veterinarian. This medication should be administered at every 30 day intervals, year-round to guarantee complete protection.  For cats over 16.5 lbs, use the appropriate combination of tubes to ensure complete protection.
Immediately before use, open the pouch and remove the applicator.  Pull back the plunger of the unit applicator slightly and remover the cap.  Hold the applicator in the upright position until ready to administer. 
Part the fur on the back of the cat's neck at the base of the head, until skin is visible.  Place the tip of the applicator vertically against the skin. Apply contents directly on the skin.  If the weight of the cat requires a second application, apply the contents in the same manner as described in the same location.  Do not massage into the skin.  Do not apply when the haircoat is wet.  For the first 60 minutes after application ensure the cat cannot lick the product from application sites on themselves or other treated animals.
Do not contact or allow children to contact the application site until dry.  Wash hands and contacted skin thoroughly with soap and water immediately after application.
Missed Doses
Give the dose as soon as you remember, unless it is time for the next dose.  Do not double dose.  If your cat has missed a dose please consult with your veterinarian.
Side Effects
Centragard™ Topical Solution is generally well tolerated in cats when given at the usual dose.  Stiff hair, a damp appearance of the hair, or a powdery residue may be observed at the application site. There are very few side effects when the drug is given a the usual dose.  The following side effects have been reported with the use of Centragard™ Topical Solution: temporary hairloss and slight inflammation or scabs at or near the application site, vomiting, diarrhea, decreased appetite, lethargy, and itchiness. 
Ensure that the cat does not ingest the product. 
Other side effects may occur. If you notice anything unusual, contact your veterinarian.
Drug & Food Interactions
There are no documented drug interactions with this medication. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely.
For topical use only. Avoid oral ingestion. For the first 60 minutes after application ensure the cat cannot lick the product from the application sites on themselves or other treated animals.  Children should not come in contact with the application site until the area is dry.  Product is highly flammable. Keep away from heat, sparks, open flame, or other sources of ignition. Avoid contact with eyes, skin, and clothing.
Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.
Adverse Reactions
If you are concerned that your pet has experienced an adverse reaction to this medication or have concerns about the product, please contact the manufacturer Boehringer Ingelheim at 888-637-4251 or contact Vetsource customer service at 877-738-4443.
Store long term at or below 86°F, excursions permitted up to 104°F. Keep this medicine out of reach of children. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.
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