Cerenia (maropitant citrate) for Dogs
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Effectively Prevents Vomiting in Dogs: Cerenia is the first FDA-approved veterinary medication to prevent vomiting safely and effectively in dogs. It also prevents vomiting due to motion sickness in dogs.* It’s available with a veterinarian’s prescription.
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#1 Choice Among Veterinarians: More veterinarians choose Cerenia over other options for the prevention of acute vomiting in dogs.1 In a study, Cerenia prevented 93% of motion sickness vomiting cases compared with 45% for placebo.2
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Convenient Dosing: Cerenia is an easy-to-administer and non-sedating tablet that is given once-daily. To prevent vomiting from car sickness, you can give Cerenia to puppies 4 months and older. For prevention of acute vomiting, you can give Cerenia to puppies 2 months and older.
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24 Hour Effectiveness: Cerenia starts working quickly to prevent your pet’s vomiting. It’s effective for about 24 hours.
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Dosing Varies Depending on Prescription: The dose of Cerenia to be given depends on whether it is being prescribed to prevent vomiting from car sickness or to prevent acute vomiting at home. Follow your vet’s instructions as prescribed.
Cerenia® (maropitant citrate) is the first FDA-approved veterinary medication to prevent vomiting safely and effectively in dogs. Cerenia also effectively prevents vomiting due to motion sickness in dogs.* It’s available with a prescription from your veterinarian. Motion sickness in dogs is a common issue pet owners face and can affect up to 48% of dogs.3 Cerenia helps you and your dog enjoy life every day, without the worry of vomiting due to car sickness. It’s a convenient, non-drowsy tablet given once a day that starts working quickly to prevent your dog’s vomiting and is effective for about 24 hours. Dosing depends on whether it’s prescribed to prevent vomiting from car sickness or to prevent acute vomiting at home so follow your veterinarian’s recommendations as prescribed. To prevent vomiting from car sickness, give your dog Cerenia with a small amount of food at least 2 hours before traveling. You can do this once a day for up to 2 days in a row. To prevent acute vomiting at home, you can give Cerenia once daily to puppies 2-7 months old for up to 5 days in a row or once daily to dogs older than 7 months, until resolution of vomiting, as prescribed by your veterinarian. Save with convenient automatic deliveries and ensure your dog is never without Cerenia for your next road trip adventure. Cerenia is eligible for Zoetis Petcare Rewards Program. Enroll today for free to earn points on every dollar spent on eligible purchases that can be redeemed for services at your vet.
IMPORTANT SAFETY INFORMATION:
Use CERENIA Tablets for acute vomiting in dogs 2 months and older, and for prevention of vomiting due to motion sickness in dogs 4 months and older. Safe use has not been evaluated in dogs with gastrointestinal obstruction, or those that have ingested toxins. Use with caution in dogs with hepatic dysfunction. In people, topical exposure may elicit localized allergic skin reactions, and repeated or prolonged exposure may lead to skin sensitization. See full Prescribing Information at
CereniaPI.com.
References
*Dramamine®, Bonine®, Benadryl® and herbal supplements have not been tested and approved by the FDA-CVM for use in dogs.
1. ZMR: Vetcove Update - Cerenia Tablets & Injection, November 2023. TI-10537
2. Conder GA, Sedlacek HS, Boucher JF, Clemence RG. Efficacy and safety of maropitant, a selective neurokinin 1 receptor antagonist, in two randomized clinical trials for prevention of vomiting due to motion sickness in dogs. J Vet Pharmacol Ther. 2008;31(6):528-32. doi: 10.1111/j.1365-2885.2008.00990.x
3. Custom Motion Sickness and Noise Aversion Omnibus Pet Owner Quantitative Research Report, December 2018.
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For
Dogs
Active ingredient(s)
Maropitant citrate
Product class
Antiemetic
Product strength & size
Cerenia tablets are scored and contain 16 mg, 24 mg, 60 mg or 160 mg of maropitant per tablet.
Please ensure the selected product and quantity are appropriate for your pet, as recommended by your veterinarian. For current availability, please refer to the product selection above.
Usage
Cerenia should be administered as directed by your veterinarian. Wash hands with soap and water after administration. Please consult your veterinarian before making any changes or discontinuing the prescribed dosing schedule.
Do not give more medication than prescribed. If you have questions about your pet’s prescribed dosing schedule (e.g., timing, interval), please contact your veterinarian.
Manufacturer Directions for Use*
Always follow your veterinarian's directions.
For acute vomiting prevention in dogs 2-7 months of age: Administer orally at a minimum dose of 2 mg/kg body weight once daily for up to 5 consecutive days.
For acute vomiting prevention in dogs 7 months of age and older: Administer orally at a minimum dose of 2 mg/kg body weight once daily until resolution of acute vomiting.
For prevention of vomiting due to motion sickness in dogs 4 months of age and older: Administer orally at a minimum dose of 8 mg/kg body weight once daily for up to 2 consecutive days; Administer a minimum of 2 hours prior to travel with a small amount of food, but refrain from a full meal.
Note: The underlying cause of acute vomiting should be identified and addressed in dogs that receive Cerenia Tablets. If vomiting persists despite treatment, the case should be reevaluated.
*Additional information may be provided within the manufacturer’s full Prescribing Information. Always follow the specific instructions provided by your veterinarian regarding your pet's care.
Storage
Store in a cool, dry place at a controlled room temperature (68°–77°F) with excursions permitted between 59°–86°F. Keep this and all other medications in a secure location out of the reach of children and animals.
Only remove 1 tablet at a time from the foil-backed blister card and return the card to the box to protect from light. Tablets should remain sealed and only taken out of the blister pack at the time of dosing. If you were instructed to split the tablets, wrap the remaining portion tightly in the blister pack foil and store securely until it is time for the next dose.
Exposure to extreme temperatures, light, or moisture can affect the integrity and effectiveness of medications. Always store this medication properly (e.g., away from the bathroom, kitchen sink, or other damp places).
Side effects
The most common side effects of this medication are anorexia (decreased appetite), depression/lethargy, hypersalivation (excessive drooling), vomiting, and diarrhea.
Contact your veterinarian immediately if your pet experiences a seizure, muscle tremors, or if any signs of an allergic reaction (e.g., facial or throat swelling, rash, difficulty breathing) occur.
The information provided above may not encompass all possible side effects. Please notify your veterinarian if your pet experiences any side effects, including those listed above, or if you notice anything unusual.
Precautions
Before using this product, please review the manufacturer’s full Prescribing Information for any relevant warnings and safety precautions.
For oral use in dogs only.
Not for use in humans. Keep this and all medications out of reach of children and animals. In case of accidental ingestion, seek medical advice. Topical exposure may elicit localized allergic skin reactions in some individuals. Repeated or prolonged exposure may lead to skin sensitization. Wash hands with soap and water after administration.
Cerenia is also an ocular irritant. In case of accidental eye exposure, flush with water for 15 minutes and seek medical attention.
The safe use of Cerenia Tablets has not been evaluated in breeding, pregnant, or lactating dogs. Discuss the risks of using this medication with your veterinarian prior to use if your pet is in one of these groups.
Do not administer this medication to animals with a known or suspected allergy/hypersensitivity to it or any of its ingredients. Allergic reactions to medications may occur. Please inform Vetsource and your veterinarian if your pet has any known sensitivities or allergies, especially to medications and supplements.
If your pet displays symptoms of an allergic reaction, discontinue therapy and call your veterinarian immediately or seek emergency veterinary attention. Symptoms may include (but are not limited to): swollen lips, tongue, face, or airways; difficulty breathing; agitation; profuse salivation; and widespread hives or itching.
Drug and food interactions
The following drugs* may have potential interactions with this medication:
azole antifungals (e.g., itraconazole, ketoconazole), calcium channel blockers (e.g., amlodipine, diltiazem), clomipramine, corticosteroids (e.g., dexamethasone, prednisone), phenobarbital, sotalol, SSRIs (e.g., fluoxetine), tramadol, and warfarin.
*NOTE: This may not be a comprehensive list. As with all medications, please consult your veterinarian if you have any questions or concerns prior to use. Contact your veterinarian if your pet experiences any unusual reactions when multiple medications and/or supplements are given together.
Please ensure your veterinarian is aware of all medications, supplements, and over-the-counter (OTC) products that your pet is currently using. Your veterinarian may prescribe multiple medications, even if a potential drug interaction may occur. In these instances, your veterinarian may adjust the dosages or monitor your pet more closely.
Adverse reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Zoetis at 1-888-963-8471 or Vetsource Pet Owner Care at 877-738-4443.
Overdose
If you have any reason to suspect accidental consumption or overdose, call your doctor/veterinarian or the appropriate poison control resource immediately.
For humans:
The national toll-free Poison Help line, 1-800-222-1222, will connect you to your local poison center in case of emergency. This service is available nationwide and in most U.S. territories.
For animals:
The ASPCA Animal Poison Control Center is available 24 hours a day, 365 days a year at 888-426-4435.
Pet Poison Helpline also provides a 24/7 animal poison control service at 855-764-7661.
*Please note: The contact information provided above is for third-party services in the event of a potential poison-related emergency. Consultation fees may apply for these services.
Disclaimer
The content provided on this page is NOT medical advice.
All content, including the images and product description above, is intended for general informational purposes only and should not be considered a substitute for professional veterinary consultation, diagnosis, or treatment.
For additional information about this product and how it fits into your pet's individual treatment plan, please consult your veterinarian.
Last revised: 6/12/2026