Virbac Corporation

Cyclavance Oral Solution

Virbac Corporation
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Description
A Chemical on the Prop 65 List
Product 
Cyclavance™ Oral Solution for Dogs
Product Information
Cyclavance™ for Dogs Oral Solution is a non-steroidal treatment for control of canine atopic dermatitis. Atopic dermatitis is a common skin disease in dogs caused by allergens, such as house dust mites or pollens, which trigger an exaggerated immune response. The disease is chronic or long-lasting and must be managed over the course of your dog’s life
For
Dogs (at least 6 months of age and weighing at least 4 lbs)
Generic Name
Cyclosporine (Modified)
Brand Name
Cyclavance™, Atopica®, Neoral®
Drug Class
Immunosuppressive
Manufacturer
Virbac
Product Description & Form
Cyclavance™ 100 mg/ml 15 ml Bottle: white (colorless to yellow) oral solution (NDC 51311-0994-15)
Cyclavance™ 100 mg/ml 50 ml Bottle: white (colorless to yellow) oral solution (NDC 51311-0994-50)
Benefits
  • Proven to be effective and safe in reducing the itch, inflammation and skin lesions associated with atopic dermatitis
  • Provides long term relief without using steroids
  • Easy to administer 
  • Dispensing system includes an adaptor cap and oral dosing syringe with marks in 0.1 ml to 3 ml increments for easy dosing with no leaks or spills
Active Ingredients
Cyclosporine
Usage
Cyclavance™ should be given orally as directed by your veterinarian. At least 1 hour before and 2 hours after feeding, administer Cyclavance™ oral solution directly into your dog’s mouth following the step-by-step instructions. Package includes a adaptor cap and oral dosing syringe with complete instructions on how to assemble the system and dose the medication. Wear gloves when administering and wash hands after handling.
Do not rinse or clean the oral dosing syringe between uses. Store the oral dosing syringe in the plastic tube between each use. 
Once opened, use contents within 12 weeks.
Missed Doses
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.
Side Effects
Side effects may include loss of appetite, vomiting, and diarrhea. Your pet may also experience liver and kidney problems. If you notice anything unusual, contact your veterinarian.
Drug & Food Interactions
The following drugs can potentially interact with cyclosporine: acetazolamide, allopurinol, amlodipine, antibiotics, carvedilol, cimetidine, ciprofloxacin/enrofloxacin, corticosteroids, digoxin, erythromycin, gentamicin, ketoconazole, methotrexate, metoclopramide, metronidazole, omeprazole, phenobarbital, and phenytoin. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Make sure to tell your veterinarian what other medication or supplements you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. 
Cautions
Cyclavance™ is not for use in breeding , pregnant or lactating dogs. Do not use  Cyclavance™ if your pet has a history of cancer. Use with caution in dogs with diabetes mellitus and renal insufficiency.
Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.
Human Exposure Warning
This medication may represent a hazard to males or females who are actively trying to conceive, women who are pregnant or may become pregnant, and women who are breast feeding, because it may be present in breast milk. Unopened, intact tablets and capsules may not pose the same degree of risk as injectable drugs that usually require extensive preparation. Cutting, crushing, or otherwise manipulating tablets and capsules will increase the risk of exposure. Wear gloves while handling this medication. Wash your hands thoroughly with soap and water after handling this medication. 
Adverse Reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Virbac at 800-338-3659 or Vetsource customer service at 877-738-4443.
Storage
Store at 68°F to 86°F in controlled room temperature. Do not refrigerate.  Keep this medicine out of reach of children. Store medication in original container. Store medication and dosing syringe securely. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.
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