Akorn, Inc.

Lactulose Solution

Akorn, Inc.
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Lactulose Solution

Product Information

Lactulose Solution is a synthetic sugar used to treat constipation. It is broken down in the colon into products that pull water out from the body and into the colon. 


Dogs and Cats

Generic Name


Brand Names

Enulose®, Cephulac®, Kristalose®

Drug Class

Ammonia Detoxicant, Osmotic Laxative

Product Flavoring

Lactulose Solution is unflavored.

Product Description & Form

*Lactulose is a generic medication, and therefore we may have different manufacturers at any given time. 

Current Manufacturer: Akorn

Lactulose 10 gm/15 ml Solution 473 ml: colorless to slightly yellow solution. (NDC 50383-0795-16)


  • Used to treat constipation
  • Used to reduce the amount of ammonia in the blood of patients with liver disease
  • Each 15 ml of solution contains 10 grams of lactulose

Active Ingredients


Inactive Ingredients

Galactose, unspecified form lactose, water, sodium hydroxide


Lactulose should be given orally as directed by your veterinarian.

Missed Doses

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.

Side Effects

Side effects may include loss of flatulence, bloated stomach and cramping. If your pet experiences diarrhea and dehydration, contact your veterinarian immediately as these may be signs of over dosage and your pet may need a lower dosage.

Other side effects may occur. If you notice anything unusual, contact your veterinarian.

Drug & Food Interactions

The following drugs can potentially interact with lactulose: antacids, other laxatives (loose stools), furosemide, and oral antibiotics. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. 


This medication does not have an FDA approved indication for use in animals, but it is a common and acceptable practice for veterinarians to prescribe this human medication for use in animals.

Lactulose may alter insulin requirements so should be carefully used in diabetic patients. Lactulose should be cautiously used in patients with preexisting fluid and electrolyte imbalances. 

Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.

Adverse Reactions

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource customer service at 877-738-4443.


Store at 59°F to 86°F in controlled room temperature. Do not freeze. Keep this medicine out of reach of children. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.

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