MERCK Animal Health

Orbax® Suspension

MERCK Animal Health
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Description
Product 
Orbax® Suspension
Product Information
Orbax® Suspension is an antibiotic used to treat skin and soft tissue infections (wounds and abscesses) in dogs & cats.  It can also be used to treat urinary tract infections (cystitis) in dogs.
For
Dogs and Cats
Generic Name
Orbifloxacin
Brand Names
Orbax® 
Drug Class
Fluoroquinolone Antibiotic
Product Flavoring
Orbax® Suspension is malt flavored.
Manufacturer
Merck
Product Description & Form
Orbax 30 mg/ml Suspension 20 ml: tan suspension. (NDC 00061-2321-01)
Benefits
  • Palatable malt flavored suspension
  • Bound to a patented taste-masking agent so it passes taste buds undetected, then is released in the low pH environment of the stomach
  • Broad spectrum antibiotic with once a day dosing
  • Ready to use, no reconstitution needed
  • No refrigeration required
  • Mess-free dispensing system 
  • Package contains a dosing syringe with marks in 0.25 ml increments up to 3 ml and bottle-syringe adaptor for easy administration
  • Each ml provides 30 mg of orbifloxacin
Active Ingredients
orbifloxacin
Inactive Ingredients
Water, DL-lactic acid, sodium hydroxide, sorbic acid, propylene glycol, silicon dioxide, barley malt syrup (NDC 00061-2321-01)
Usage
Orbax® Suspension should be administered as directed by your veterinarian. Shake well before use.
Before Initial Use: Remove the cap and insert the syringe adaptor by pressing firmly into top of bottle. Insert the syringe tip into the adaptor opening and invert the bottle. Withdraw the required amount of medication with the calibrated syringe. After use, replace cap, leaving adaptor in the bottle, and rinse the syringe with water. 
Give this medication to your pet for the time period prescribed by your veterinarian, even if it appears the pet is feeling better. This will help to ensure the infection is all cleared up.
Missed Doses
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.
Side Effects
Serious side effects are not expected when used at therapeutic doses. Possible side effects may include vomiting, soft stools, reduced appetite, lethargy, itching and rashes. If these symptoms persist and appear troublesome, contact your veterinarian. Orbifloxacin and other quinolones have been shown to cause cartilage damage in immature growing animals and use should be avoided in young animals (<8 months small breeds, <18 months large breeds). The use of fluoroquinolones in cats has been reported to adversely affect the retina. Blindness has been reported in cats that have used orbifloxacin at higher than normal doses. The following reactions are rare, but if the pet experiences convulsions, confusion, or an allergic reaction such as irregular breathing, rash, fever, puffiness and swelling around the face contact your veterinarian immediately.
Other side effects may occur. If you notice anything unusual, contact your veterinarian.
Drug & Food Interactions
The following drugs can potentially interact with quinolones: antacids, cimetidine, sucralfate, nitrofurantoin, cyclosporine, theophylline, and probenecid. Certain compounds (e.g., vitamins, antacids, iron) may interfere with the absorption of fluoroquinolone antibiotics. Administration of this drug with vitamin/mineral supplements and/or antacids should be avoided or discussed with your veterinarian. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together. 
Make sure to tell your veterinarian what other medication you are giving your pet. Quite often your veterinarian may prescribe two different medications, and a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. 
Cautions
Orbifloxacin and other quinolones have been shown to cause arthropathy in immature animals of most species tested. Compounds (e.g., sucralfate, antacids, and multivitamins) containing divalent and trivalent cautions (e.g., iron, aluminum, calcium, magnesium, and zinc) may substantially interfere with the absorption of quinolones resulting in a decrease in product bioavailability. The use of fluoroquinolones in cats has been reported to adversely affect the retina and should be used with caution in cats.
Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.
Adverse Reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Merck at 800-224-5318 or Vetsource customer service at 877-738-4443.
Storage
Store at 36°F to 77°F in controlled room temperature. Keep this medicine out of reach of children. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.
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