PRN® Pharmacal

Proin® Chewable Tablets

PRN® Pharmacal
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Proin® Chewable Tablets 
Product Information
Proin® is a chewable tablet used for the management and treatment of canine urinary incontinence.  These are the immediate release chewable tablets.
*Proin® is a controlled substance medication in the following states: AR, IA, LA, MS, WV.  All electronically prescribed orders shipping to these states will require verbal authorization with the prescriber prior to dispensing. 
*The following states require the pet owner date of birth to be on file prior to dispensing: AR, IN, MS, WV.
Generic Name
Brand Names
Drug Class
Sympathomimetic, Alpha Adrenergic Stimulant
Product Flavoring
Proin® Chewable Tablets are chicken liver flavored.
*Contains yeast, soy, and chicken.
PRN Pharmacal
Product Description & Form
Proin® 25 mg Chewable Tablets 60 ct & 180 ct: 16 mm, brown, round tablet, scored in half, imprinted with Proin;25. (NDC 49427-0315-48, 49427-0315-50)
Proin® 50 mg Chewable Tablets 60 ct & 180 ct: 16 mm, brown, round tablet, scored in half, imprinted with Proin;50. (NDC 49427-0141-48, 49427-0141-50)
Proin® 75 mg Chewable Tablets 60 ct & 180 ct: 16 mm, brown, round tablet, scored in half, imprinted with Proin;75. (NDC 49427-0316-48, 49427-0316-50)
  • Used to treat dogs unable to hold their urine (urinary incontinence)
Active Ingredients
Phenylpropanolamine hydrochloride
Inactive Ingredients
Stearic acid, soy protein, silicon dioxide, whey, garlic, chicken liver.
Proin® should be given orally as directed by your veterinarian.
Missed Doses
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.
Side Effects
Your pet may experience a loss of appetite, restlessness, irritability, tremors, fast heart rate, high blood pressure and urine retention. If these symptoms appear excessive or persist, contact your veterinarian. If your pet becomes nauseous, looses its appetite, vomits, has a fast heart rate, appears disoriented and the pupils dilate, contact your veterinarian.
Other side effects may occur, if you notice anything unusual, contact your veterinarian.
Drug & Food Interactions
The following drugs can potentially interact with phenylpropanolamine: tricyclic antidepressants, non-steroidal anti-inflammatory agents, halogenated anesthetic agents, ephedrine, chlorpromazine, monoamine oxidase inhibitors, reserpine, and ganglionic blocking agents. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
Make sure to tell your veterinarian what other medication or supplements you are giving your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may be anticipated. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. 
For use in dogs only. Not for human use. Keep out of reach of children and pets. The safe use of Proin® in dogs used for breeding purposes, during pregnancy or in lactating bitches, has not been evaluated. Proin® may cause elevated blood pressure and should be used with caution in dogs with pre-existing heart disease, high blood pressure, liver disease, kidney insufficiency, diabetes, glaucoma, and other conditions associated with high blood pressure.
Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.
Adverse Reactions
If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer PRN Pharmacal at 850-476-9462 or Vetsource customer service at 877-738-4443.
Store at 68°F to 77°F in controlled room temperature, excursions permitted between 59°F to 104°F. Keep this medicine out of reach of children. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.
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$35.27 - $130.87