Merial Limited

ProZinc® Insulin

Merial Limited
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$186.57 - $329.28
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Product Details

ProZinc® Insulin

Product Information

ProZinc® Insulin, a protamine zinc recombinant human insulin, provides fast, effective results for hyperglycemia in pets with diabetes. ProZinc® works quickly and effectively to regulate blood glucose levels in cats and dogs.

ProZinc® Insulin requires refrigeration; all orders must be shipped overnight at an additional charge and are not eligible for free shipping. Orders only ship Monday-Thursday and will not be processed the day before a major holiday. 


Cats, Dogs

Product Description

Once mixed (after gently rolling the vial), Prozinc® has a white, cloudy appearance.  Clumps or visible white particals can form in insulin suspensions: do not use the product if clumps or visible white particles persist after gently rolling the vial.


  • ProZinc® insulin releases slowly over time to help maintain a stable, consistent blood glucose level throughout the day.
  • ProZinc® insulin provides fast, effective results for hyperglycemia in pets with diabetes.

Active Ingredients

protamine zinc recombinant human insulin

How Supplied

10 ml multi-dose vial; Use within 60 days of first puncture.

20 ml multi-dose vial; Use within 80 days of first puncture.


ProZinc® Insulin should be administered as directed by your veterinarian.

Mix the insulin by gently rolling in your hand before each dose. Do not shake the vial.

Only use U-40 insulin syringes to measure this product accurately (sold separately).  Use of a syringe other than U-40 insulin syringe will result in incorrect dosing.

Injections should be given subcutaneously, just under the skin either along the back of the neck or on the side of the pet. Be sure to rotate injection sites to prevent skin problems at the injection site. Pinch a fold in the skin to create a small space for the needle. Insert the needle into the center of the fold as instructed by the veterinarian. Inject the drug by pushing the plunger as far as it will go. Withdraw the needle and be careful to not stick yourself. Dispose the needle immediately in a proper sharps disposal container.

Insulin requires refrigeration and must be shipped overnight. 

Injectable medications require needles and syringes.  Those items are purchased separately.  Please ask your veterinarian for a recommendation for the correct needle/syringe sizes for your pet.

Side Effects

Possible side effects of insulin therapy include hypoglycemia. Signs include hunger, lethargy, nervousness, vocalization, anxiety, muscle tremors or trembling, weakness, ataxia/unsteadiness. If there are signs of hypoglycemia, offer the pet some food or oral glucose. Positive response should occur within one to two minutes, then contact your veterinarian.

Other side effects may occur. If you notice anything changes in your pet, contact your veterinarian.


This medication is indicated for the reduction of hyperglycemia and hyperglycemia-associated clinical signs in cats and dogs with diabetes mellitus.  Inform your veterinarian prior to use of this medication if your pet has low blood sugar (hypoglycemia). Do not switch from one type insulin to another unless under the direction of a veterinarian as making the switch may require an adjustment in the dose.

Make sure to tell your veterinarian what other medication or supplements you are giving your pet. Dietary changes may also affect insulin requirements. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. The following drug interactions that may occur with insulin include: Beta-adrenergic blockers, clonidine, and digioxin. Drugs that may increase hypoglycemic activity of insulin (resulting in low blood sugar) include: captopril, enalapril, alcohol, anabolic steroids, beta-adrenergic blockers, MAOI’s, guanethidine, phenylbutazone, sulfinpyrazone, sulfonamides, tetracycline, and aspirin, or other salicyclates. Drugs that may decrease hypoglycemic activity of insulin (resulting in high blood sugar) include: epinephrine, estrogen/progesterone combinations, furosemide, glucocorticoids, isoniazide, phenothiazine derivatives, thiazide diuretics, and thyroid hormones. Serum potassium levels can fluctuate in combination with digoxin and insulin and additional monitoring may be needed. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Allergic reactions to medications may occur. Be sure to inform VetSource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.

Adverse Reactions

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact the manufacturer Boehringer Ingelheim at 888-637-4251 or Vetsource customer service at 877-738-4443.


Store in an upright position under refrigeration at 36-46 degree F.  Do not freeze.  Protect from light.  Keep out of reach of children and pets. Use the 10 ml vial within 60 days of first puncture.  Use the 20 ml vial within 80 days of first puncture.

$186.57 - $329.28