Apotex Corp

Selegiline Capsules

Apotex Corp
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Selegiline Capsules

Product Information

Selegiline is a daily medication for treatment of Cushing's disease and for the treatment of Canine Cognitive Dysfunction Syndrome (CCDS). CCDS is an age-related neurologic syndrome characterized by various cognitive impairments such as disorientation, reduced social interaction, changes in sleep or activity patterns, and loss of housetraining.



Generic Name


Brand Names


Drug Class

Monoamine Oxidase Inhibitor (MAOI)

Product Description & Form

*Capsule size, color, shape, markings, or coating may be different from description. Selegiline is a generic medication, and therefore we may have different manufacturers at any given time. Capsules may vary in appearance. 

Current Manufacturer: Apotex

Selegiline 5 mg Capsules 60 ct: 16 mm, white & blue capsule, not scored, imprinted with APO;055. (NDC 60505-0055-01)


  • Used to treat Cushing's Disease and Canine Cognitive Dysfunction Syndrome

Active Ingredients

Selegiline hydrochloride

Inactive Ingredients

Anhydrous lactose, anhydrous citric acid, microcrystalline cellulose, steric acid, talc, gelatin, FD&C Blue No 1, titanium dioxide, ammonia, ferrosoferric oxide, alcohol, isopropyl alcohol, potassium hydroxide, propylene glycol, water, shellac, butyl alcohol. (NDC 60505-0055-01)


Selegiline should be given orally as directed by your veterinarian. Do not stop giving the medication unless advised by your veterinarian.

Missed Doses

Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give 2 doses at once.

Side Effects

Side effects may include vomiting, diarrhea, restlessness, repetitive movements, drowsiness, salivation, loss of appetite, diminished hearing, itching, licking, shivers. Observe the pet carefully for other side effects and contact your veterinarian if you notice anything unusual.

Drug & Food Interactions

Selegiline belongs to a class of drugs called Monoamine Oxidase Inhibitors (MAOI) it should not be given with antidepressants, amitraz, or ephedrine.

The following drugs can potentially interact with selegiline: amitriptyline, atropine, clomipramine, dextromethorphan, diphenoxylate, other MAO inhibitors, metoclopramide, mirtazapine, phenylpropanolamine, ondansetron, fluoxetine, and tramadol. Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.

Make sure to tell your veterinarian what other medication you are giving to your pet. Quite often your veterinarian may prescribe two different medications, even if a drug interaction may occur. In this case, your veterinarian may vary the dose and/or monitor your pet more closely. 


This medication does not have an FDA approved indication for use in animals, but it is a common and acceptable practice for veterinarians to prescribe this human medication for use in animals.

Allergic reactions to medications may occur. Be sure to inform Vetsource and your veterinarian if your pet has any known drug sensitivities or allergies. If your pet displays symptoms of an allergic reaction, call your veterinarian immediately or go to a veterinary emergency clinic. Symptoms may include but are not limited to: swollen lips, tongue, face, airways; difficulty breathing; agitation; profuse salivation; vomiting; widespread hives and itching.

Adverse Reactions

If you are concerned that your pet has experienced an adverse reaction to this medication, please contact Vetsource customer service at 877-738-4443.


Store at 68°F to 77°F in controlled room temperature. Keep this medicine out of reach of children. Store in a childproof container. Store this medicine in a cool, dry place at room temperature. Store away from heat and direct sunlight. Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.

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